Why Powders?
Powders are becoming the ‘gold standard’, since:

• ..Liquids do not ‘dwell’ effectively in the upper nose
• ..Small drug molecules, proteins and peptides are
....formulated for this route
• ..Line extensions/evergreening for:
...........- .ADHD, bipolar disorder, enzyme inhibitors,
..............hormone replacement, pain control, psychosis
...........- .Anti-infective vaccines and some DNA vaccines
...........- .Intranasal delivery of particles around 20 micron
• ..Medicines with bioavailability problems by other routes:
...........- .First pass metabolism, formulation problems,
..............G/I side effects
• ..Generic medication
...........- .Innovative larger companies seeking higher
..............value differentiators

Performance
• ..Particle sizes around 15 micron
• ..Very low ullage
• ..Narrow cone angle
• ..Potentially lower doses
• ..Adaptability for a wide range of dosing applications

Safety & Packaging
• ..Efficacy incorporates fail-safe technology with locking
....feature and evidence of actuation
• ..Over-wrap for additional security
• ..Pharmas can affix labels on a flat surface or
....emboss with a logo